AI Model Predicts Immunotherapy Response in Melanoma Patients

The discovery of immune checkpoint inhibitors (ICIs) revolutionized the treatment of advanced melanoma, however, there is currently no easy way to predict patient response  or their risk for immune-related toxicities without conducting RNA sequencing – a method rarely found at community oncology clinics. Researchers report an emerging technique that aims to solve this problem by …

Assessing Cancer Risk Associated with Immunosuppressive Therapies 

Over the past few decades, the dermatologic care of inflammatory skin conditions has been transformed through the growing use of small molecules disease-modifying anti-rheumatic drugs (DMARDs) and targeted biologic therapies. However, alongside the tremendous benefits offered by these therapeutic agents are concerns regarding potential adverse effects, in particular associated risks of cancer development. The controversial …

Using Zinc for the Treatment of Acne Vulgaris

As an essential nutrient, zinc supports the immune system while reducing inflammatory cytokine activity making it a potential therapeutic method for many dermatologic conditions although, it has been most widely studied in the treatment of acne vulgaris.  Prior studies have reported that zinc can decrease oil production, protect against bacterial infection, and decrease cutaneous inflammation, …